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EMS
 
Definition:
Biology Glossary search by EverythingBio.com
 
     
 
  • EMS alkylates guanine at the O6 position, forming O6-ethylguanine (Et-G), which base pairs with thymine
  • Two rounds of DNA replication change a Et-G—C base pair to a A—T pair
  • Cells also have repair enzymes that can remove the thyl group from Et-G
  • EMS mutagenesis can also lead to deletions
 
     


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