MDA5 and LGP2: Accomplices and Antagonists of Antiviral Signal Transduction.
J Virol. 2014 August
Paramyxovirus V Protein Interaction with the Antiviral Sensor LGP2 Disrupts MDA5 Signaling Enhancement but Is Not Relevant to LGP2-Mediated RLR Signaling Inhibition.
J Virol. 2014 July
High-Density Nucleosome Occupancy Map of Human Chromosome 9p21-22 Reveals Chromatin Organization of the Type I Interferon Gene Cluster.
J Interferon Cytokine Res. 2014 March
Small RNA Profiling of Influenza A Virus-Infected Cells Identifies miR-449b as a Regulator of Histone Deacetylase 1 and Interferon Beta.
PLoS One. 2013 September
Extensive Cooperation of Immune Master Regulators IRF3 and NFκB in RNA Pol II Recruitment and Pause Release in Human Innate Antiviral Transcription.
Cell Rep. 2013 September
MicroRNA profiling of Sendai virus-infected A549 cells identifies miR-203 as an interferon-inducible regulator of IFIT1/ISG56.
J Virol. 2013 August
Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway.
JAKSTAT. 2013 July
A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory.
PLoS Biol. 2013 March
Detection of activated STAT proteins.
Methods Mol Biol. 2013
Amino acid requirements for MDA5 and LGP2 recognition by paramyxovirus V proteins: a single arginine distinguishes MDA5 from RIG-I.
J Virol. 2013 March
ATP hydrolysis enhances RNA recognition and antiviral signal transduction by the innate immune sensor, laboratory of genetics and physiology 2 (LGP2).
J Biol Chem. 2013 January
Influenza A Virus Infection of Human Respiratory Cells Induces Primary MicroRNA Expression.
J. Biol Chem. 2012 July
Activation of RIG-I-like receptor signal transduction.
Biochem Mol Biol 2012 March
Impaired cellular responses to cytosolic DNA or infection with Listeria monocytogenes and vaccinia virus in the absence of the murine LGP2 protein.
PLoS One 2011 April
Dissociation of paramyxovirus interferon evasion activities: universal and virus-specific requirements for conserved V protein amino acids in MDA5 interference.
J. Virol 2010 Aug.
Regulating immune response using polyvalent nucleic acid-gold nanoparticle conjugates.
Mol Pharm. 2009 Nov.
Paramyxovirus Disruption of Interferon Signal Transduction: STATus Report.
J Interferon Cytokine Re. 2009 Aug.
A shared interface mediates paramyxovirus interference with antiviral RNA
helicases MDA5 and LGP2.
Virol. 2009 July
Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins
MDA5, RIG-I, and LGP2.
JBC. 2009 April
A point mutation, E95D, in the mumps virus V protein disengages STAT3 targeting from STAT1 targeting.
J. Virol. 2009 April
Negative regulation of cytoplasmic RNA-mediated antiviral signaling.
Cytokine. 2008 Sep.
STAT2 is a primary target for measles virus V protein-mediated alpha/beta interferon signaling inhibition.
J Virol. 2008 Sep.
Enabled interferon signaling evasion in an immune-competent transgenic mouse model of parainfluenza virus 5 infection.
Virology. 2007 Oct
Relationships between Viruses and Cancer: For better and For Worse.
The Journal. Robert H. Lurie Comprehensive Cancer Center of Northwestern University.
Vol. XI (2)Page 13 2007.
Tracking of human Y receptors in living cells--a fluorescence approach.
Peptides. 2007 Feb.
RNA- and virus-independent inhibition of antiviral signaling by RNA helicase LGP2.
J Virol. 2006 Dec
A novel role for viral-defective interfering particles in enhancing dendritic cell maturation.
J Immunol. 2006 Oct
Measles virus V protein inhibits p53 family member p73.
J Virol. 2006 Jun
Carbonyl- and sulfur-containing analogs of suberoylanilide hydroxamic acid: Potent inhibition of histone deacetylases.
Bioorg Med Chem. 2006 May on beta.
Sci STKE. 2004 Nov 23
Positive and negative regulation of the innate antiviral response and beta interferon gene expression by deacetylation
Mol Cell Biol. 2006 April