Sigma-Aldrich shRNA is available as prepackaged lentiviral transduction particles
Sigma-Aldrich is a global supplier of the comprehensive MISSION(TM) shRNA library through participation in The RNAi Consortium (TRC). Individual clones, gene target sets, gene families and druggable and whole genome libraries are available as lentiviral transduction particles, purified plasmid DNA or frozen bacterial glycerol stocks harboring sequence-verified shRNA. Each gene is represented by a target set that consists of an average of 3-5 individual constructs or clones targeting different regions of the gene sequence. Click here to begin your search. (Please note that clicking this link will take you to Sigma's world-wide website.)

Sigma-Aldrich RNAi Partnership Program

Northwestern has signed on to Sigma-Aldrich RNAi Partnership Program. All researchers at participating institutions receive the following:

• Human and Mouse libraries, gene families and single clones on demand at discounted rates ( Glycerol, Plasmid or Lentiviral Particle formats)
• Custom GFP Vectors, large scale/high titer Lentivirus, custom gene family sets, and a large selection of positive / negative shRNA controls in the Lentiviral Particle format.
• Early access to new technologies developed through collaborations with Oxford, Benitec, and TRC.
• Freedom to operate under Sigma’s exclusive rights to the broad intellectual property portfolio licensed from Benitec and Oxford BioMedica through purchase of Sigma’s Functional Genomics products at a discounted price.
• Access to Functional Genomics product portfolio at special partnership pricing for products including: siRNA, Quantitative PCR probes and reagents and protein quantitation kits and reagents.
• Dedicated support team for ordering and technical service.

Price structure for RNAi Partnership Program

Orders should be placed directly with Sigma.  It is not necessary to contact Northwestern's RNAi Core for this pricing.

Please contact our Sigma research specialist Melissa King [Melissa.King@sial.com] with any questions.