menu home members research publications links internal site

Publications from the Sontheimer Lab Gerbasi, V. R., Preall, J. B., Golden, D. E., Powell, D. W., Cummins, T. D., and Sontheimer, E. J. (2011) Blanks, a nuclear siRNP component, is required for Drosophila spermiogenesis. Proceedings of the National Academy of Sciences U. S. A., in press (published online 2/7/2011) Sontheimer, E. J. and Marraffini, L. A. (2010) Microbiology: Slicer for DNA. Nature 468, 45-46 Gerbasi, V. R., Golden, D. E., Hurtado, S. B., and Sontheimer, E. J. (2010) Proteomic identification of Drosophila siRNA-associated factors. Molecular & Cellular Proteomics 9, 1866-1872. Marraffini, L. A. and Sontheimer, E. J. (2010) CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea. Nature Reviews Genetics 11, 181-190. Marraffini, L. A. and Sontheimer, E. J. (2010) Self vs. non-self discrimination during CRISPR RNA-directed immunity. Nature 463, 568-571. Lee, Y. S., Pressman S., Andress, A. P., Kim, K., White, J. L., Cassidy, J. J., Li, X., Lubell, K., Lim, D. H., Cho, I. S., Nakahara, K., Preall, J. B., Bellare, P., Sontheimer, E. J. and Carthew, R. W. (2009) Silencing by small RNAs is linked to endosome trafficking. Nature Cell Biology 11, 1150-1156. Marraffini, L. A. and Sontheimer, E. J. (2009) Invasive DNA, chopped and in the CRISPR. Structure 17, 783-787. Carthew, R. W., and Sontheimer, E. J. (2009). Origins and mechanisms of miRNAs and siRNAs. Cell 136, 642-655. Marraffini, L. A., and Sontheimer, E. J. (2008). CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA. Science 322, 1843-1845. Golden, D. E., Gerbasi, R. V., and Sontheimer, E. J. (2008). An inside job for siRNAs. Mol. Cell 31, 309-312. Bellare, P., Small, E. C., Huang, X., Wohlschlegel, J. A., Staley, J. P., and Sontheimer, E. J. (2008). A role for ubiquitin in the spliceosome assembly pathway. Nature Structural & Molecular Biology 15, 444-451. Bellare, P., and Sontheimer, E. J. (2007). A fork in the road for microRNAs. Nature Structural & Molecular Biology 14, 684-686. Preall, J. B., He, Z., Gorra, J., and Sontheimer, E. J. (2006). Short interfering RNA strand selection is independent of dsRNA processing polarity during RNAi in Drosophila. Curr. Biol. 16, 530-535. Bellare, P., Kutach, A. K., Rines, A., Guthrie, C., and Sontheimer, E. J. (2006). Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p. RNA 12, 292-302. Preall, J. B., and Sontheimer, E. J. (2005). RNAi: RISC gets loaded. Cell 123, 543-545. Pham, J. W., and Sontheimer, E. J. (2005). Molecular requirements for RISC assembly in the Drosophila RNAi pathway. J. Biol. Chem. 280, 39278-39283. Pellino, J. L., Jaskiewicz, L., Filipowicz, W., and Sontheimer, E. J. (2005). A Dicer-containing complex interacts with short interfering RNAs in human cell extracts. RNA 11, 1719-1724. Sontheimer, E. J. and Carthew, R. W. (2005). Silence from within: Endogenous siRNAs and miRNAs. Cell 122, 9-12. Sontheimer, E. J. (2005). Assembly and function of RNA silencing complexes. Nature Reviews Molecular and Cellular Biology 6, 127-138. Pham, J. W. and Sontheimer, E. J. (2004). The making of an siRNA. Molecular Cell 15, 163-164. Sontheimer, E. J. and Carthew, R. W. (2004). Argonaute journeys into the heart of RISC. Science 305, 1409-1410. He, Z., and Sontheimer, E. J. (2004). SiRNAs and miRNAs: A meeting review on RNA silencing. RNA 10, 1165-1173. Pham, J. W., Radhakrishnan, I., and Sontheimer, E. J. (2004). Thermodynamic and structural characterization of 2'-nitrogen-modified RNA duplexes. Nucleic Acids Research 32, 3446-3455. Pham, J. W., Pellino, J. L., Lee, Y. S., Carthew, R. W., and Sontheimer, E. J. (2004). A Dicer-2-dependent 80S complex cleaves targeted mRNAs during RNAi in Drosophila. Cell 117, 83-94. Lee, Y. S., Nakahara, K., Pham, J. W., Kim, K., He, Z., Sontheimer, E. J., and Carthew, R. W. (2004). Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 117, 69-81. Sontheimer, E. J. (2003). R2D2 leads the silencing trigger to mRNA's death star. Cell 115, 132-133. Sontheimer, E. J. (2001). The spliceosome shows its metal. Nature Structural Biology 8, 11-13. Molecular Biosciences This page was last modified on: 2011/09/22 All information contained is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 2.5 License About this web site