Publications

DNA topoisomerases Catalytic RNA molecules Spectrin

DNA topoisomerases

  1. Lima, C.D., Wang, J.C. and Mondragón, A. Three-dimensional structure of the 67K N-terminal fragment of  E. coli DNA topoisomerase I.  Nature, 367, 138-146, 1994.
  2. Sharma, A., Hanai, R. and Mondragón, A. Crystal Structure of the Amino Terminal Fragment of Vaccinia Virus DNA Topoisomerase I at 1.6 Å Resolution.  Structure, 2,767-777, 1994.
  3. Lue, N., Sharma, A., Mondragón, A. and Wang, J.C. A 26 kDa yeast DNA topoisomerase I fragment: crystallographic structure and mechanistic implications.  Structure, 3, 1315-1322, 1995.
  4. Mondragón, A. and DiGate, R. Structure of E. coli DNA topoisomerase III, Structure, 7,1373-1383,1999.
  5. Feinberg, H., Lima, C.D. and Mondragón, A. Conformational changes in E. coli DNA topoisomerase I. Nature Struct. Biol., 6, 918-922, 1999.
  6. Feinberg, H., Changela, A. and Mondragón, A. Protein-nucleotide interactions in E. coli DNA topoisomerase I. Nature Struct. Biol., 6, 961-968, 1999.
  7. Li, Z., Mondragón, A., Hiasa, H., Marians, K.J., and DiGate, R.J. Identification of a unique domain essential for Escherichia coli DNA topoisomerase III-catalysed decatenation of replication intermediates. Mol. Microbiol., 35, 888-895, 2000.
  8. Li, Z., Mondragón,A, and DiGate, R. The mechanism of type IA topoisomerase-mediated DNA topological transformations. Molecular Cell, 7, 301-307, 2001.
  9. Changela, A., DiGate, R. and Mondragón, A. Crystal structure of a complex of a type IA DNA topoisomerase with a single-stranded DNA molecule. Nature, 411, 1077-1081, 2001.
  10. Perry, K. and Mondragón, A. Biochemical Characterization of an Invariant Histidine Involved in Escherichia coli DNA Topoisomerase I Catalysis. J. Biol. Chem., 277, 13237-13245, 2002.
  11. Perry K. and Mondragón A. Structure of a complex between E. coli DNA topoisomerase I and single-stranded DNA. Structure, 11, 1349-1358, 2003.
  12. Patel, A. Shuman, S., and Mondragón, A. Crystal structure of bacterial type Ib DNA topoisomerase reveals a preassembled active site in the asbence of DNA. J. Biol. Chem. 281, 6030-6037, 2006.
  13. Taneja, B., Patel, A., Slesarev, A., and Mondragón, A. Structure of the N-terminal fragment of topoisomerase V reveals a new family of topoisomerases. EMBO J., 25, 398-408, 2006.
  14. Changela, A., DiGate, R.J., and Mondragón, A, Structural Studies of E. coli Topoisomerase III-DNA Complexes Reveal A Novel Type IA Topoisomerase-DNA Conformational Intermediate, J. Mol. Biol., 2007, in press.

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Catalytic RNA molecules

  1.  Krasilnikov AS, Yang X, Pan T, Mondragón A. 2003. Crystal structure of the specificity domain of ribonuclease P., Nature, 421. 760-764, 2003.
  2. Krasilnikov, A.S. and Mondragón, A. On the occurrence of the T-loop RNA folding motif in large RNA molecules. RNA, 9, 640-643, 2003.
  3. Krasilnikov, A.S., Xiao,Y., Pan,T. and Mondragón,A. Basis for Stuctural Diversity in Homologous RNAs, Science, 306, 104-107, 2004.
  4. Torres-Larios A., Swinger K. K., Krasilnikov A. S., Pan T., Mondragón A. Crystal structure of the RNA component of bacterial ribonuclease P. Nature. 437, 584-587, 2005.
  5. Torres-Larios A., Swinger K. K., Pan T., Mondragón A. Structure of ribonuclease P - a universal ribozyme. Curr. Opin. Struct. Biol. 16, 327-335, 2006.
  6. Baird N.J., Srividya N., Krasilnikov A.S., Mondragon A., Sosnick T.R., Pan T., Structural basis for altering the stability of homologous RNAs from a mesophilic and a thermophilic bacterium. RNA, 12, 598-606, 2006
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Spectrin

  1. Grum, V.L., Li, D., MacDonald,R.I. and Mondragón, A. Structures of two repeats of spectrin suggest models of flexibility. Cell, 98, 523-535, 1999.
  2. Kusunoki, H., MacDonald, R.I., and Mondragón, A. Structural Insights into the Stability and Flexibility of Unusual Erythroid Spectrin Repeats. Structure, 12, 645-656, 2004.
  3. Kusunoki, H., Minasov, G., MacDonald, R.I., and Mondragón, A. Independent Movement, Dimerization and Stability of Tandem Repeats of Chicken Brain a-Spectrin, J. Mol. Biol., 344, 495-511, 2004.

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