About the Group

The Rosenzweig group is focused on understanding metalloprotein function on the molecular level.  We use X-ray crystallographic, spectroscopic, biochemical, and molecular biological approaches to attack problems at the forefront of bioinorganic chemistry.  Projects in the laboratory are divided into two areas, metalloenzymes and metal trafficking proteins, with an increasing focus on integral membrane proteins.  Specific areas of interest include biological methane oxidation, metal uptake and transport, and oxygen activation by metalloenzymes.

We are in the Department of Molecular Biosciences at Northwestern University (Evanston campus).  We are also part of the Department of Chemistry.

Latest News

December 2014
Joe received a Fletcher Prize for Undergraduate Research for work he did with Tom. Congratulations!

November 2014
Ingrid has left us for a position at the Heinrich-Heine-Univerisät Düsseldorf. Congratulations and good luck!

October 2014
Amy was inducted into the American Academy of Arts and Sciences.

Amy received the Ivano Bertini Award at the Ninth International Copper Meeting. Congratulations!

September 2014
Grace received the Rappaport Award for Research Excellence. Congratulations!

Rahul Purohit has joined the group as a postdoctoral researcher. Rahul received his PhD in chemistry for work done in the lab of Dr. William Montfort at the University of Arizona.

Megen's paper on the structure of methanol dehydrogenase is published in Biochemistry. Read the article.

August 2014
Sarah successfully defended her PhD thesis. Congratulations!

Soo Ro has joined the group as a graduate student. Soo obtained her undergraduate degree in integrative biology from the University of California, Berkeley.

July 2014
Megen's paper on EPR studies of pMMO metal centers is published in JACS. Read the article.

Megen has left us to become an Assistant Professor at Appalachian State University.. Congratulations and good luck!

June 2014
Sarah's paper on the effects of zinc on pMMO is published in the Journal of Biological Chemistry. Read the article.

May 2014
Amy received the Royal Society of Chemistry Joseph Chatt Award.

April 2014
Amy was elected to the American Academy of Arts and Sciences.

March 2014
Aaron's article on the diversity of metal-transporting ATPases is published in the Journal of Biological Inorganic Chemistry. Read the article.

February 2014
Tom's article on conservation of the B subunit in particulate methane/ammonia monooxygenases is published in Proteins: Structure, Function, and Bioinformatics. Read the article.

September 2013
Eliza's article on a nickel- and iron-transporting P1B-type ATPase is published in Metallomics. Read the article.

Eliza has left us to take up a postdoctoral research position at Argonne National Laboratory. Good luck!

August 2013
Laura Dassama joined the group as a postdoctoral fellow. Laura comes from the joint lab of Profs. Carsten Krebs and J. Martin Bollinger Jr. at Penn. State.

Laura and Amie's article on class 1c ribonucleotide reductases is published in Biochemistry. Read the article.

July 2013
Amie has left us to become an Assistant Professor at Penn State. Congratulations and good luck!

Tom's article on a nitrite reductase involved in nitrifier denitrification is published in the Journal of Biological Chemistry. Read the article.

May 2013
Tom successfully defended his PhD thesis. Congratulations!

April 2013
Eliza successfully defended her PhD thesis. Congratulations!

March 2013
Amy was invested as the Weinberg Family Distinguished Professor of Life Sciences.

Amy's News and Views article on soluble methane monooxygenase is published in Nature Chemical Biology. Read the article.

February 2013
Grace's paper on detection of new methanobactins in genomes is published in BMC Biology. Read the article.

January 2013
Tom Lawton was elected Chair of the 2015 Bioinorganic Chemistry Graduate Research Seminar.

Rosenzweig lab alums Raquel Lieberman (Georgia Tech), Matt Sazinsky (Pomona College), and Liliya Yatsunyk (Swarthmore College) were all promoted to Associate Professor with tenure. Congratulations!