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Dorsal-Ventral Patterning Genes
 
Definition:
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  • The dorsal/ventral boundary of the developing wing imaginal disc structures the growth of the entire wing.
  • Dorsal-ventral patterning genes
    • Transcription factors: brinker, dorsal, bagpipe, CrebA, C-terminal binding protein, Medea, nejire, pannier, schnurri, single minded, snail, tinman, twist, zerknüllt
    • Ventral lateral system or spitz group: pointed, rhomboid, single minded, sichel (maternal), spitz, Star
    • Secreted factors: dpp, folded gastrulation, screw, short gastrulation, twisted gastrulation, tolloid, tolloid related-1
    • Receptors for DPP: punt, saxophone, thick veins
    • DPP pathway: Medea, MAD
  • Regulation of genes involved in dorsal-ventral patterning
    • Dorsoventral patterning of the Drosophila embryo is initiated by a broad Dorsal nuclear gradient, which is regulated by a conserved signaling pathway that includes the Toll receptor and Pelle kinase.
 
     


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