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A convention used to describe
features of a DNA sequence, gene or mRNA related to the position and
direction (5' to 3') of transcription by RNA polymerase or translation
by the ribosome. Downstream (or 3' to) is in the direction of transcription
(or translation) whereas upstream (5' to) is in the direction from
which the polymerase (or ribosome) has come. Conventionally DNA sequences,
gene maps and RNA sequences are drawn with transcription (or translation)
from left to right and so downstream is towards the right. |
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