|
AKA: Morpholino oligo
"Morpholino oligos are so named because they
are assembled from four different Morpholino subunits,
each of which contains one of the four genetic
Bases (A denine, Cytosine, Guanine, and Thymine)
linked to a 6-membered morpholine ring.
Eighteen to 25 subunits of these four subunit
types are joined in a specific order by
non-ionic phosphorodiamidate intersubunit linkages
to give a Morpholino oligo."
"These Morpholino oligos with their 6-membered
morpholine backbone moieties joined by non-ionic
linkages afford substantially better antisense
properties than do RNA, DNA, and their analogs
having 5-membered ribose or deoxyribose backbone
moieties joined by ionic linkages."
From: http://www.morpholino.com
- a great site about morpholinos
|
|