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- Mutations in segment polarity genes cause a disruption in pattern
formation in each segment of the fly.
- Are known to regulate each other’s expression
- Gene products are believed to contribute to the specification of individual
pattern elements (Bejsovec and W., 1993)
- Eg: hh, smo, fu, ci
- Through genetic analysi: involved in the transduction of either the
Hh signal or the signal encoded by the wg gene
- Mutations in hh, smo, fu, ci eliminate wg transcription at para-segmental
borders
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