| 
         
          |  |   
          |  |   
          |  |   
          | 
               
                |  | 
 
 
                     
                      | Signal 
                        Amplification |   
                      | 
                           
                            |  |  |  |   
                            |  |  |  |   
                            |  | The use of specific detection methodologies to directly 
                        increase the signal in proportion to the amount of target 
                        in the reaction. Examples include the use of branched 
                        DNA probes that contain a reporter group or enzyme amplification. |  |   
                            |  |  |  |  
 |  
 |  |  |   
          | 
 
 
 
 |  |