{Models}
Symbol:
- AKA: spatula
- In the TEA/ATTS domain transcription factor family (Campbell et al.
1991, 1992)
{Links}
|
Flybase ID: {Flybase_ID} |
| Synonyms: {Name}
|
{GadFly} |
| Function: {Short_Function} |
{LocusLink} |
| Keywords: {Keywords} |
{Interactive_Fly} |
{Summary}
|
- transcription factor
- Vg and Sd function coordinately to control the expression of genes
required for wing development (00002, 00003)
|
- Vg is required to maintain sd expression in the wing progenitor cells,
and sd is similarly required for the maintenance of elevated vg expression
(Williams et al. 1993)
|
- Binds directly to Vg [(00002) reference also contains approximate
binding region] and as a complex bind to wing-specific enhancers (00003)
|
- nuclear
- A subset of cells within almost all imaginal discs normally express
sd (Campbell et al. 1992)
|
- Can lead to loss of wing tissue, similar to vg mutations (Campbell
et al. 1991, 1992; Williams et al. 1991, 1993)
|
- Has similar phenotype to sd or vg loss-of-fxn mutants; it acts as
a dominate negative
|