Dong Zhao

moved to Department of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin
as Postdoctoral Fellow

Education and Experience

• B.S., Shanghai Medical University, China, Dept. of Pharmacology (1992)

• Research Associate, Cardiovascular Institute, Beijing Medical University (Now Medical Center of Peking University) (1992-1995)
  Poly-peptides regulation in hypertension; Cellular protective effect of polyamine

• Research Fellow, Department of Pharmacology, University of Aarhus (1995-1996)
  Alpha-1 adrenoceptor antagonist characterization; mechanism of myogenic response

• Ph.D., University of Wisconsin-Madison, (2002) Molecular & Environmental Toxicology
  (Advisor: Dr. Colin R. Jefcoate)
  Thesis: Steroidogenesis regulation; StAR mRNA stability; arsenite toxicity & MAPKs pathway; StAR protein processing

Other Publications

• Dong Zhao, Young-Cheul Kim, and Colin Jefcoate.(2002) StAR mRNA is regulated by a specialized degradation mechanism that is enhanced by 3’-UTR sites and is tightly coupled to ongoing transcription and translation. Submitted to Endocrinology

• Dong Zhao, Hongwei Xue and Colin Jefcoate. (2002) Sodium arsenite activates and then suppresses both adrenal steroidogenic acute regulatory protein (StAR) expression and cholesterol metabolism. Submitted to Endocrinology

• Irina Artemenko, Dong Zhao, Dale Hales, Karen Hales, and Colin Jefcoate. (2001) Mitochondria processing of newly synthesized steroidogenic acute regulatory protein (StAR), but not total StAR, mediates cholesterol transfer to cytochrome P450 side chain cleavage enzyme in adrenal cells. Journal of Biological Chemistry: 276, 46583-96

• Colin R Jefcoate, Irina Artemenko, and Dong Zhao. (2000) Relationship of StAR expression to mitochondrial cholesterol transfer and metabolism. Endocrine Research: 26, 663-680.

• Irina Artemenko, Dong Zhao, and Colin Jefcoate. (1999) Mitochondrial processing of StAR mediates cholesterol metabolism in adrenal cells independent of total StAR. Molecular Steroidogenesis 29, 301-302.

• Qing Tian, Dong Zhao, Jifeng Zhang, et al. (1996) Investigation on inhibition of biological effects of endothelin. Science in China. Series C, 39, 207-216.

• Dong Zhao, Qing Tian, Yuntao Zhao, et al. (1995) A study on hypotensive mechanisms of adrenomedullin. Acta Physiologica Sinica, 47: 218-224.

• Qing Tian, Dong Zhao, Dunyong Tan, et al. (1995) The vasodilator effect of human adrenomedullin(13-52) on hypertensive rats. Canadian Journal of Physiology & Pharmacology. 73, 1065-1069.

• Dong Zhao, Jifeng Zhang, Dunyong Tan, et al. (1995) Protective effect of putrescine on isoproterenol-induced myocardic damage. Chinese Pharmacological Bulletin, 11, 77-79.

• Dong Zhao, Pinghu Liu, Aihua Fu, et al. (1994) Protective effect of putrescine on oleic acid-induced respiratory distress syndrome (RDS). Chinese Journal of Tuberculosis and Respiratory Disease, 17, 156-158

How to reach me

E-mail