Genes / Proteins | Definitions | Models | Developmental Models | General Concepts | Contribute/Corrections | Links | Protocols | Home
     
 

Achaete
a proneural gene

Apterous
a LIM-homeodomain protein

Araucan
a member of the iroquois complex (Iro-C)

Armadillo
.

Blistered
Drosophila serum response factor (D-SRF)

Casein Kinase 1
a kinase

Caupolican
a member of the iroquois complex (Iro-C)

CBP
a transcriptional co-activator

Costal-2
kinesin like protein involved in hedgehog signaling and acts by anchoring Cubitus interruptus in the cytoplasm

Cubitus interruptus
Zinc finger transcription factor that mediates Hedgehog signaling

Cul1
functions as a scaffold protein within the SCF complex which functions as ubiquitin E3 ligase

Cut
transcription factor - homeodomain - cut domain - mediates choice between chordotonal sense organ and external sensory organ fate - also involved in wing and follicle cell morphogenesis

Decapentaplegic
ligand with tgf-beta homology involved early to establishes embryonic dorsal/ventral and later patterns appendages

Delta
transmembrane - EGF family - Notch ligand - important in establishing neural cell fates

Dishevelled
.

Dispatched
patched family protein regulating Hedgehog release

EGFR
transmembrane receptor- tk - EGF-R homology - during oogenesis helps set up egg polarity, determines the identity of cells in the ectoderm; during larval stages participates in the development of the eye and wing.

Engrailed
transcription factor - homeodomain - engrailed class - segment polarity gene - involved in compartment identity and boundary formation

Extramacrochaetae
a helix-loop-helix protein lacking a basic motif shown to be involved in the control of cell proliferation in the wing

Fused
serine/threonine kinase - segment polarity gene - cytoplasmic component of Hedgehog signaling pathway

Gli proteins
mamalian homologues of Ci

GSK3
serine/threonine kinase - cytoplasmic component of Hedgehog and Wingless signaling pathway

Hedgehog
a segment polarity intercellular signaling protein

Knot
required for the formation of the hypopharyngeal lobe, the proper development of the larval head skeleton, and suppresses vein formation between veins 3 and 4

Mirror
a member of the iroquois complex (Iro-C)

Mothers against Dpp
novel protein - downstream of DPP - Smad family members convey TGF¨ signals from their receptors to the nucleus

nejire
(see CBP)

Nedd8
ubiquitin-like small protein modifier

Notch
.

Openbrain
.

Optomotor-blind
.

Patched
transmembrane - segment polarity gene - receptor for Hedgehog

PKA
.

PKAc
.

PKAr
.

Rhomboid
serine protease - transmembrane protein involved with Epidermal growth factor receptor signaling - required for the production or processing of Spitz, the Egfr ligand

Roc1
a Ring finger protein in SCF complex

Scalloped
.

Scute
a proneural gene

Serrate
.

Serum response factor
AKA: blistered

Sex-lethal
.

Shavenbaby
.

Skp1
an adaptor protein that links Cullins with the F-box protein

Smoothened
.

Sonic Hedgehog
mammalian Hedgehog homologue

Spitz
.

Supernumerary limbs
F-box protein involved in Ci degradation

Suppressor of fused
novel PEST domain containing protein involved in Hedgehog signaling

Vein
a secreted neuregulin-like molecule that activates EGFR signaling and is a candidate moledule for establishing the notum

Vestigial
a wing specific gene

Wingless
.
 
     


 Genes / Proteins  |  Definitions  |  Models  |  Developmental Models  |  General Concepts  |  Contribute/Corrections  |  Links  |  Protocols  |  Home